Document Detail


Lack of association between iron status at birth and growth of preterm infants.
MedLine Citation:
PMID:  17063240     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the association between iron status at birth and growth of preterm infants. METHODS: Ninety-five premature babies (26 to 36 weeks of gestational age) born from July 2000 to May 2001 in a public hospital in Rio de Janeiro, Southeastern Brazil, were followed up for six months, corrected by gestational age. Iron measurements at birth were available for 82 mothers and 78 children: hemoglobin, hematocrit, mean corpuscular volume and plasma iron. All children received free doses of iron supplement (2 mg/kg/day) during the follow-up period and up to two years of age. Multivariate linear regression analyses with repeated measurements were performed to assess factors associated to linear growth. RESULTS: Growth was more pronounced up to 40 weeks of gestational age, increasing about 1.0 cm/week and then slowing down to 0.75 cm/week. The multivariate analysis showed growth was positively associated with birth weight (0.4 cm/100 g; p<0.001) and negatively associated with gestational age at birth (-0.5 cm/week; p<0.001). There was no association between cord iron and mother iron measurements and growth (p>0.60 for all measures). Only two children had anemia at birth, whereas 43.9% of mothers were anemic (hemoglobin <11 g/dl). Also, there was no correlation between anemia indicators of mothers and children at birth (r<0.15; p>0.20). CONCLUSIONS: Maternal anemia was not associated with anemia in preterm infants and iron status of mothers and children at birth was not associated with short-term growth of preterm infants.
Authors:
Rosely Sichieri; Vania Matos Fonseca; Daniel Hoffman; Nadia Maria F Trugo; Aníbal Sanchez Moura
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista de saúde pública     Volume:  40     ISSN:  0034-8910     ISO Abbreviation:  Rev Saude Publica     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-10-25     Completed Date:  2007-03-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0135043     Medline TA:  Rev Saude Publica     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  641-7     Citation Subset:  IM    
Affiliation:
Instituto de Medicina Social, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, Brasil. sichieri@ims.uerj.br
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MeSH Terms
Descriptor/Qualifier:
Anemia, Iron-Deficiency / blood,  diagnosis*
Anthropometry
Biological Markers / blood
Epidemiologic Methods
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature / growth & development*
Infectious Disease Transmission, Vertical*
Iron / administration & dosage,  blood*
Male
Sex Factors
Socioeconomic Factors
Chemical
Reg. No./Substance:
0/Biological Markers; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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