Document Detail


Lack of additional effect of adjunct of assisted ventilation to pulmonary rehabilitation in mild COPD patients.
MedLine Citation:
PMID:  12113387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Different modalities of assisted ventilation improve breathlessness and exercise tolerance in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to evaluate the effects of the addition of assisted ventilation during exercise training on the outcome of a structured pulmonary rehabilitation programme (PRP) in COPD patients. Thirty-three male patients with stable COPD (mean (SD) forced expiratory volume in 1 s (FEV1) 44 (16) % pred), without chronic ventilatory failure, undergoing a 6-week multidisciplinary outpatient PRP including exercise training, were randomised to training during either mask proportional assist ventilation (PAV: 18 patients) or spontaneous breathing (SB: 15 patients). Assessment included exercise tolerance, dyspnoea, leg fatigue, and health-related quality of life (HRQL). Five out of 18 patients (28%) in the PAV group dropped out due to lack of compliance with the equipment. Both groups showed significant post-PRP improvements in exercise tolerance (peak work rate difference: 20 (95% Cl 2.4-37.6) and 14 (3.8% CI to 24.2) W in PAV and SB group, respectively), dyspnoea and leg fatigue, but not in HRQL, without any significant difference between groups. It is concluded that with the modality and in the patients assessed in this study assisted ventilation during training sessions included in a multidisciplinary PRP was not well tolerated by all patients and gave no additional physiological benefit in comparison with exercise training alone.
Authors:
L Bianchi; K Foglio; R Porta; R Baiardi; M Vitacca; N Ambrosino
Related Documents :
18403667 - Are patients with copd more active after pulmonary rehabilitation?
18924297 - Reliability of verbal descriptors of dyspnea and their relationship with perceived inte...
11834677 - A systematic review of the effects of bronchodilators on exercise capacity in patients ...
12391117 - Effects of exercise and beta 2-agonists on lung function in chronic obstructive pulmona...
3177687 - Exercise training attenuates baroreflex regulation of nerve activity in rabbits.
20382667 - Basal and insulin-stimulated pyruvate dehydrogenase complex activation, glycogen synthe...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Respiratory medicine     Volume:  96     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-07-12     Completed Date:  2002-07-30     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  359-67     Citation Subset:  IM    
Affiliation:
Salvatore Maugeri Foundation IRCCS, Pulmonary Rehabilitation Unit, Scientific Institute of Gussago, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Combined Modality Therapy
Dyspnea / therapy
Exercise Therapy*
Exercise Tolerance
Humans
Leg
Male
Middle Aged
Muscle Fatigue
Patient Dropouts
Pulmonary Disease, Chronic Obstructive / physiopathology,  rehabilitation,  therapy*
Respiration, Artificial*
Respiratory Mechanics
Respiratory Muscles / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of ozone on bronchial mucosal inflammation in asthmatic and healthy subjects.
Next Document:  Stability of time trade-off utilities for health states associated with the treatment of prostate ca...