Document Detail


Laboratory testing for prothrombotic states: clinical utility.
MedLine Citation:
PMID:  12932317     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is possible to detect a genetic contribution to venous thrombosis in a significant proportion of patients. This has led to a huge expenditure in clinical time and health resource. However, the gains to be made from the uncritical investigation of the causes of venous thromboembolism are limited and the approach raises significant issues in relation to the appropriateness of this form of genetic testing. In contrast, there are some acquired prothrombotic states that should be identified because the risk of further thrombosis may be sufficient to influence therapy. These states include antiphospholipid syndrome, myeloproliferative disorders, and cancer.
Authors:
Michael Greaves; H G Watson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current hematology reports     Volume:  2     ISSN:  1540-3408     ISO Abbreviation:  Curr. Hematol. Rep.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-22     Completed Date:  2003-11-12     Revised Date:  2006-07-31    
Medline Journal Info:
Nlm Unique ID:  101151358     Medline TA:  Curr Hematol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  429-34     Citation Subset:  IM    
Affiliation:
Department of Medicine and Therapeutics, University of Aberdeen, Polwarth-Forresterhill AB252ZD, Scotland. m.greaves@abdn.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Humans
Risk Factors
Thrombophilia / diagnosis*,  drug therapy,  genetics

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