| Laboratory identification of cryoglobulinemia from automated blood cell counts, fresh blood samples, and blood films. | |
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MedLine Citation:
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PMID: 11939736 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Four cases showing different means to detect cryoglobulins are reported: effects on blood cell counts performed on 2 technologically different automated hematology instruments and microscopic features in fresh blood samples and on May-Grünwald-Giemsa-stained bloodfilms. These cases were chosen for their instructive value in depicting all artifacts associated with cryoglobulins. Laboratory recognition of the cryoglobulins is important to correct factitious results with automated blood cell counters, mainly pseudoleukocytosis and pseudothrombocytosis. Moreover cryoglobulin-induced laboratory artifacts may be the first factor prompting the assessment for cryoglobulinemia and the diagnosis of the underlying cause. |
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Authors:
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Anne Fohlen-Walter; Christine Jacob; Thomas Lecompte; Jean-François Lesesve |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 117 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 2002 Apr |
Date Detail:
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Created Date: 2002-04-09 Completed Date: 2002-04-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 606-14 Citation Subset: AIM; IM |
Affiliation:
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Hematology Laboratory, Centre Hospitalier Universitaire Nancy, Vandoeuvre, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autoanalysis Blood Cell Count* Cryoglobulinemia / blood*, complications, diagnosis* Erythrocyte Count Humans Leukocyte Count Lymphoma, B-Cell / complications Multiple Myeloma / complications Platelet Count |
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