Document Detail

Laboratory findings in four cases of adult botulism suggest colonization of the intestinal tract.
MedLine Citation:
PMID:  3290234     Owner:  NLM     Status:  MEDLINE    
There was laboratory evidence of intestinal colonization in four cases of adult botulism confirmed by the Centers for Disease Control. No performed toxin was detected in available foods, but Clostridium botulinum was isolated from foods in two instances. Botulinal toxin was detected in the sera of all four patients, in one case at 47 days after ingestion of suspected food. C. botulinum was demonstrated in the stool of all four patients and persisted for 119 days after the onset of illness in one patient. Two patients had surgical alterations of the gastrointestinal tract, which may have promoted the colonization. The apparent lack of ingestion of performed toxin in these cases and the persistence of botulinal toxin or C. botulinum, or both, for long periods in three of the patients suggest that colonization of the intestinal tract occurred.
L M McCroskey; C L Hatheway
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  26     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-08-01     Completed Date:  1988-08-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1052-4     Citation Subset:  IM    
Division of Bacterial Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
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MeSH Terms
Botulinum Toxins / blood
Botulism / microbiology*
Clostridium botulinum / growth & development*
Intestines / microbiology*
Reg. No./Substance:
0/Botulinum Toxins

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