| Laboratory and field evaluations of a repellent soap containing diethyl toluamide (DEET) and permethrin against phlebotomine sand flies (Diptera: Psychodidae) in Valle del Cauca, Colombia. | |
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MedLine Citation:
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PMID: 7872447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The repellency and insecticidal efficacy of Nopikex, a soap formulation containing 20% diethyl toluamide and 0.5% permethrin, was evaluated against a laboratory colony of phlebotomine sand flies (Lutzomyia longipalpis). The repellency of Nopikex soap was also compared with that of a placebo soap against another species (Lu. youngi) in a forest near Tulua, Valle del Cauca, Colombia. In laboratory trials of the soap, no reduction in repellency was seen 4 hr after application, but within 8 hr, repellency decreased significantly to 67.0% of the initial value (P < 0.05) based on calculations of the coefficient of protection (CP). Under field conditions, the soap gave up to 100% protection immediately after application, but within 4 hours its CP value had decreased to a median value of only 44.3%. The placebo soap was also found to be somewhat repellent when compared with no treatment, giving a median CP value of 67.7 immediately after application. No significant mortality was seen in sand flies within 24 hr of exposure to the soap in the laboratory, even in those that had fed on protected volunteers. |
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Authors:
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B Alexander; H Cadena; M C Usma; C A Rojas |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 52 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-03-30 Completed Date: 1995-03-30 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 169-73 Citation Subset: AIM; IM |
Affiliation:
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Fundacion Centro Internacional de Entrenamiento e Investigaciones Medicas, Cali, Colombia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Colombia DEET Female Humans Insect Bites and Stings / prevention & control* Insect Repellents* Insect Vectors* Insecticides Leishmaniasis / prevention & control* Male Permethrin Psychodidae* Pyrethrins Soaps Sweating Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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I-P50 AI-30603-01/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Insect Repellents; 0/Insecticides; 0/Pyrethrins; 0/Soaps; 134-62-3/DEET; 52645-53-1/Permethrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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