| Laboratory diagnosis of infectious diarrhoea syndrome; a three years study in two hospitals of infectious diseases. | |
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MedLine Citation:
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PMID: 20361527 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infectious diarrhoea is a syndrome caused by a variety of bacterial, viral and parasitic organisms which represents a major cause of morbidity and mortality all over the world. The wide diversity of etiological agents impairs the surveillance and the diagnosis and affects the correct treatment applied to reduce the long-term complications. Besides well known enteric pathogens such as Salmonella, Shigella and Yersinia, a high number of emergent and re-emergent aetiologies are now recognised to be at the origin of diarrhoea. The lack of a correct diagnostic algorithm and adequate methods of analyses leads to under-evaluation and incertitude in an important number of clinical cases. Our study was designed as a complex analysis of the stool specimens collected from the patients, in the purpose to improve the laboratory diagnostic and to enhance the number of confirmed cases of infectious diarrhoea. A number of 756 samples from inpatients with diarrhoea were tested targeting pathogenic and opportunistic bacteria, viruses and parasites by classical and molecular methods. We documented that, in case of non-Salmonella, non-Shigella, non-Yersinia diarrhoea, the quality of diagnostic was improved by increasing the percentage of positive specimens to 22.49% compared to 11.12% when only bacteria, 5.56% when only viruses and 4.10% when only parasites were investigated. The laboratory data are of great value in evaluating the diarrhoea syndrome offering the documentation for an accurate epidemiological response and an adequate treatment. |
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Authors:
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Maria Damian; Dorina Tatu-Chi?oiu; Codru?a-Romani?a Usein; Gabriela Opri?an; Andi-Marian Palade; Sorin Dinu; Camelia Szmal; Simona Adriana Ciontea; Stefania Ceciu; Maria Condei; Ana Persu; Anda Baicu?; Mariana Pop; Ionela Neagoe; Dan Steriu; Radu Codreanu; Marian Graur; Michaela Carmen Cretu; Suzana Cilievici; Maria Nica; Alexandru Ecovoiu; Lucian Gavrili |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Roumanian archives of microbiology and immunology Volume: 68 ISSN: 1222-3891 ISO Abbreviation: Roum Arch Microbiol Immunol Publication Date: 2009 Apr-Jun |
Date Detail:
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Created Date: 2010-04-05 Completed Date: 2010-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204717 Medline TA: Roum Arch Microbiol Immunol Country: Romania |
Other Details:
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Languages: eng Pagination: 89-94 Citation Subset: IM |
Affiliation:
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National Institute of Research-Development for Microbiology and Immunology Cantacuzino, Bucharest, Romania. mdamian@cantacuzino.ro |
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| MeSH Terms | |
Descriptor/Qualifier:
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Bacterial Infections
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epidemiology* Diarrhea / epidemiology*, microbiology, parasitology, virology Feces / microbiology, parasitology, virology Female Humans Laboratory Techniques and Procedures Longitudinal Studies Male Parasitic Diseases / epidemiology* Romania / epidemiology Virus Diseases / epidemiology* |
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