| Labor and delivery characteristics and the risk of germinal matrix hemorrhage in low birth weight infants. | |
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MedLine Citation:
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PMID: 2002199 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the influence of labor and delivery events on the risk of germinal matrix hemorrhage in preterm newborns, we conducted a review of data collected on 449 babies who weighed 1.5 kg or less. Babies delivered vaginally were more likely to have germinal matrix hemorrhage than were babies delivered abdominally (odds ratio, 2.5; 95% confidence interval, 1.4,3.3). Among babies delivered vaginally, the risk of germinal matrix hemorrhage was increased by 39% if labor lasted more than 12 hours. Among babies delivered abdominally, the occurrence of any labor was accompanied by a 150% increased risk of germinal matrix hemorrhage. The only indication for abdominal delivery associated with an increased risk of germinal matrix hemorrhage was impending amnionitis (odds ratio, 2.6; 95% confidence interval, 1.2,5.7), whereas the only indication associated with a decreased risk was preeclampsia (odds ratio, 0.2; 95% confidence interval, 0.6). Epidural and local anesthesia were associated with a reduced risk of germinal matrix hemorrhage among babies delivered abdominally. We conclude that delivery practices, or their indications, appear to influence the risk of germinal matrix hemorrhage in low birth weight babies. |
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Authors:
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A Leviton; T Fenton; K C Kuban; M Pagano |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of child neurology Volume: 6 ISSN: 0883-0738 ISO Abbreviation: J. Child Neurol. Publication Date: 1991 Jan |
Date Detail:
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Created Date: 1991-04-15 Completed Date: 1991-04-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 35-40 Citation Subset: IM |
Affiliation:
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Neuroepidemiology Unit, Children's Hospital, Boston, MA 02115-5747. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Hemorrhage
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etiology* Cerebral Ventricles Cesarean Section Extraction, Obstetrical* Female Fetal Growth Retardation / etiology Humans Infant, Low Birth Weight / physiology* Infant, Newborn Infant, Premature, Diseases / etiology* Obstetric Labor Complications / etiology* Pregnancy Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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HD 06276/HD/NICHD NIH HHS; NS 20658/NS/NINDS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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