Document Detail

Labor induction with 25-microg misoprostol vaginal capsules.
MedLine Citation:
PMID:  19797903     Owner:  NLM     Status:  In-Process    
AIM: To evaluate the success rate and the safety profile of labor induction with a new misoprostol formulation - vaginal capsules of 25 microg of misoprostol. METHODS: Labor induction was performed in 250 singleton term pregnancies; 149 (59.6%) were nulliparous. Vaginal capsules of 25 microg of misoprostol were placed in the posterior vaginal fornix every 6 h. Success rate, contractility and fetal heart rate abnormalities and fetal outcomes were evaluated. RESULTS: The success rate of labor induction was 97.6%. The average number of vaginal administrations was 1.5. The mean interval between induction and active labor was 10 h and 20 min and the average length of labor was 15 h and 35 min. The cesarean section rate was 18.8%. There were 15 cases of tachysystole, 3 cases of hypertonus and 1 case of hyperstimulation syndrome. There were no adverse neonatal outcomes. CONCLUSIONS: This study allowed to conclude that labor induction with vaginal capsules of 25 microg of misoprostol is associated with an excellent success rate and safety profile.
Susana Santo; Regina Lourenço; Mónica Centeno; Luísa Pargana; Nuno Clode; Helena Ferreira; Luís M da Graça
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Publication Detail:
Type:  Journal Article     Date:  2009-09-30
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  68     ISSN:  1423-002X     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  272-5     Citation Subset:  IM    
Copyright Information:
2009 S. Karger AG, Basel.
Department of Obstetrics, Gynecology and Reproductive Medicine, Hospital Santa Maria, Lisbon, Portugal.
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