| Labial salivary gland biopsy in Sjögren's syndrome. | |
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MedLine Citation:
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PMID: 1603205 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Labial salivary gland histopathology has long been considered to be the most disease-specific single test for diagnosis of Sjögren's syndrome. However, the diagnostic yield of widely used grading systems of focal lymphocytic sialoadenitis is rather low. Determination of the percentages IgA-, IgG-, IgM-, kappa-, and lambda-containing plasma cells in minor salivary glands obtained from a lower lip biopsy has recently been shown to be extremely valuable in Sjögren's syndrome, not only for diagnosis, but also for prognosis with regard to the development of systemic monoclonal lymphoproliferative disease. This technique greatly improves the value of labial salivary gland biopsy in Sjögren's syndrome. |
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Authors:
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C Bodeutsch; P C de Wilde; L Kater; R J Hené; F H van den Hoogen; L B van de Putte; G P Vooijs |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The Netherlands journal of medicine Volume: 40 ISSN: 0300-2977 ISO Abbreviation: Neth J Med Publication Date: 1992 Apr |
Date Detail:
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Created Date: 1992-07-16 Completed Date: 1992-07-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0356133 Medline TA: Neth J Med Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 148-57 Citation Subset: IM |
Affiliation:
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Department of Pathology, University Hospital Nijmegen, Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Humans Immunoglobulins Lymphocytes Salivary Glands, Minor / immunology, pathology* Sjogren's Syndrome / immunology, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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