Document Detail


Labelling of uric acid and allantoin in different purine organs and urine of the rat.
MedLine Citation:
PMID:  8795700     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied the incorporation of 14C-formate into uric acid and allantoin in different organs (liver, lung, kidney, spleen), isolated hepatocytes, perfused liver and urine of the rat. Allantoin had a higher specific radioactivity than uric acid after 14C-formate load in the liver in vivo. This was found to be a strictly hepatic phenomenon and not due to the influence of other tissues.
Authors:
M Pizzichini; M L Pandolfi; L Arezzini; L Terzuoli; L Fe; F Bontemps; G Van den Berghe; E Marinello
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Life sciences     Volume:  59     ISSN:  0024-3205     ISO Abbreviation:  Life Sci.     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-21     Completed Date:  1996-10-21     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0375521     Medline TA:  Life Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  893-9     Citation Subset:  IM    
Affiliation:
Istituto di Biochimica e di Enzimologia, Università di Siena, Italy.
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MeSH Terms
Descriptor/Qualifier:
Allantoin / metabolism*,  urine
Animals
Carbon Radioisotopes*
Formic Acids / metabolism*
Isotope Labeling*
Kidney / metabolism
Kinetics
Liver / metabolism
Lung / metabolism
Male
Rats
Rats, Wistar
Spleen / metabolism
Uric Acid / metabolism*,  urine
Chemical
Reg. No./Substance:
0/Carbon Radioisotopes; 0/Formic Acids; 64-18-6/formic acid; 69-93-2/Uric Acid; 97-59-6/Allantoin

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