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Labeling of multiple cell lines using a new iron oxide agent for cell tracking by MRI.
MedLine Citation:
PMID:  22144030     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Stem cells, cancer cells and immune cells were labeled by co-incubation with a new ultra-small iron oxide nanoparticle called Molday ION Rhodamine-B (MIRB). Iron staining, fluorescence imaging, transmission electron microscopy and flow cytometry were used to assess cell viability, function and labeling efficiency. This study has shown that MIRB can be used to label both adherent and nonadherent cell lines, with high viability and loading levels sufficient for their detection in vivo by MRI at 3 T. Copyright © 2011 John Wiley & Sons, Ltd.
Authors:
C McFadden; C L Mallett; P J Foster
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Contrast media & molecular imaging     Volume:  6     ISSN:  1555-4317     ISO Abbreviation:  Contrast Media Mol Imaging     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101286760     Medline TA:  Contrast Media Mol Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  514-22     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 John Wiley & Sons, Ltd.
Affiliation:
Imaging Research Laboratory, Robarts Research Institute, The University of Western Ontario, 100 Perth Dr., Rm 1200B, London, ON, Canada.
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