Document Detail


Labeled citrate metabolism in bone fractures and impaired innervation.
MedLine Citation:
PMID:  14534619     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Changes in (14)C incorporation into regenerate after bone fracture and impairment of mandibular innervation, and injection of [3-(14)C]cytrate corresponded to the stages of reparative osteogenesis: after 1 week (14)C incorporation in the cellular-fibrous callus surpassed its release, after 2 weeks the rates of (14)C incorporation and release in the chondroid callus become similar, and after 4 weeks the release of the label predominated in the primary bone callus. Denervation reduced (14)C incorporation into regenerate, which impaired bone remodeling. Citrate in the bones is characterized by high metabolic activity.
Authors:
Yu A Petrovich; R P Podorozhnaya; S M Kichenko; I M Dmitriev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  136     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-10-09     Completed Date:  2004-10-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-7     Citation Subset:  IM    
Affiliation:
Moscow State Medical Stomatological University.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone and Bones / innervation*,  metabolism*
Carbon / metabolism
Citrates / metabolism*
Femur / innervation,  metabolism,  pathology
Fractures, Bone*
Mandible / innervation
Models, Chemical
Osteogenesis
Rats
Time Factors
Chemical
Reg. No./Substance:
0/Citrates; 7440-44-0/Carbon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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