| Label-free detection with surface plasmon resonance imaging. | |
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MedLine Citation:
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PMID: 21370074 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Sensors based on surface plasmon resonance have demonstrated, over the last 2 decades, to be an effective method of studying biomolecular interactions without the need for labeling. Recently, it has been adapted to high-throughput use for imaging microarray binding in real time. This provides a promising platform - a label-free protein microarray system - for the study of disease. In this example, antibody microarrays are used to efficiently profile the secretion of proteins from a cell line exposed to varying concentrations of a toxic compound. |
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Authors:
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Christopher Lausted; Zhiyuan Hu; Leroy Hood |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 723 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 321-33 Citation Subset: IM |
Affiliation:
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Institute for Systems Biology, Seattle, WA, USA, clausted@systemsbiology.org. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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