Document Detail

LDL and HDL oxidation and fatty acid composition in vegetarians.
MedLine Citation:
PMID:  11463997     Owner:  NLM     Status:  MEDLINE    
The oxidation of low-density lipoproteins (LDL) and high-density lipoproteins (HDL) and fatty acid composition, which may affect the resistance of lipoproteins to oxidation, were determined in 24 lacto-ovo vegetarians. Vegetarian diets contain more essential polyunsaturated fatty acids (PUFAs). Therefore, the relationship between LDL and HDL oxidation resistance measured by the kinetics of the formation of fatty acid conjugated dienes (lag time, maximal rate of oxidation and maximal amount of conjugated dienes), LDL and HDL fatty acid composition and vitamin E content were evaluated. All parameters of in vitro oxidation were significantly lower in HDL when compared with LDL. The relative values of arachidonic, dihomo-gamma-linoleic and docosahexaenoic acid were significantly higher in HDL, alpha-linolenic acid content significantly lower, when compared with LDL; the peroxidizability index was significantly higher in HDL. The content of vitamin E was found more than 2-fold lower in HDL particles. The results show the importance of fatty acid composition in the resistance of LDL and HDL to oxidation and from this aspect, the composition of LDL isolated from vegetarians seems to be more favourable compared to HDL.
A Nagyová; M Krajcovicová-Kudlácková; J Klvanová
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of nutrition & metabolism     Volume:  45     ISSN:  0250-6807     ISO Abbreviation:  Ann. Nutr. Metab.     Publication Date:  2001  
Date Detail:
Created Date:  2001-07-20     Completed Date:  2001-09-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8105511     Medline TA:  Ann Nutr Metab     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  148-51     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic.
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MeSH Terms
Antioxidants / analysis
Diet, Vegetarian*
Fatty Acids / analysis*
Fatty Acids, Unsaturated / administration & dosage
Lipoproteins, HDL / blood,  metabolism*
Lipoproteins, LDL / blood,  metabolism*
Reg. No./Substance:
0/Antioxidants; 0/Fatty Acids; 0/Fatty Acids, Unsaturated; 0/Lipoproteins, HDL; 0/Lipoproteins, LDL

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