| LDH isozymes in transplantable hamster tumours with different histogenesis and differentiation. | |
| | |
MedLine Citation:
|
PMID: 7271428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
LDH isozymes were assayed by polyacrylamide gel electrophoresis in 6 long-term transplantable skin tumours in Syrian hamsters. The percentages of the M-subunits were as follows: in a slow growing fibrosarcoma with abortive differentiation and producing lung metastases -- 63.3; in two well differentiated squamous cell carcinomas with moderate growth -- 79.8 and 74.9; in a slow growing and metastasizing melanotic melanoma -- 67.7; in undifferentiated amelanotic and depigmented melanomas with very fat growth -- 72.8 and 77.4. Therefore no consistent relationship has emerged between histogenesis, growth rate, differentiation and metastases of the studied neoplasms from one side and their LDH isozyme pattern -- on the other. |
| | |
Authors:
|
I G Nicolov; I N Chernozemsky; T Petkova-Bocharova; I I Stoichev |
Related Documents
:
|
12196718 - Analysis of gene expression involved in brain metastasis from breast cancer using cdna ... 2583868 - Unique patterns of brain metastasis produced by different human carcinomas in athymic n... 683618 - Incidence of subclinical metastasis in stage i and ii ovarian carcinoma. 19708318 - Breast metastasis from colonic primary: a case report and review of the literature. 10029438 - Immunohistochemical evaluation of k-ras, p53, and her-2/neu expression in hyperplastic,... 21992498 - Epigenetic events associated with breast cancer and their prevention by dietary compone... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Archiv für Geschwulstforschung Volume: 51 ISSN: 0003-911X ISO Abbreviation: Arch. Geschwulstforsch. Publication Date: 1981 |
Date Detail:
|
Created Date: 1981-10-14 Completed Date: 1981-10-14 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0372411 Medline TA: Arch Geschwulstforsch Country: GERMANY, EAST |
Other Details:
|
Languages: eng Pagination: 174-8 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Carcinoma, Squamous Cell / enzymology Cell Line Cricetinae Female Fibrosarcoma / enzymology Isoenzymes L-Lactate Dehydrogenase / metabolism* Male Melanoma / enzymology Mesocricetus Neoplasm Staging Neoplasm Transplantation Neoplasms, Experimental / enzymology Skin Neoplasms / enzymology*, pathology |
| Chemical | |
Reg. No./Substance:
|
0/Isoenzymes; EC 1.1.1.27/L-Lactate Dehydrogenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparative studies on the contamination of foods by cancerogenic hydrocarbons in the Soviet Union a...
Next Document: Carcinogenicity in BD-IX rats of 7 homologues of N-nitroso-N-n-alkylureas in different stages of pos...