| LDH isoenzymes in CSF in the diagnosis of neonatal brain damage. | |
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MedLine Citation:
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PMID: 3766114 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lactate dehydrogenase isoenzymes in cerebrospinal fluid were measured during the first 24 h of life in 25 asphyctic neonates. The infants were subjected to clinical and developmental examinations for a mean follow-up period of 15.2 months. The mean values for cerebrospinal LDH2(MH3) and LDH3(M2H2) isoenzymes were significantly higher in asphyctic infants who died from hypoxic-ischemic encephalopathy or who survived but suffered neurologic sequelae, than they were in those asphyctic infants who survived and were normal in the follow-up studies. Therefore, the authors conclude that the lactate dehydrogenase isoenzyme pattern in cerebrospinal fluid may be of value when assessing anoxic brain damage. |
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Authors:
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F Fernández; J Quero; A Verdú; M C Ferreiros; E Daimiel; M C Roche |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica Volume: 74 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 1986 Jul |
Date Detail:
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Created Date: 1986-11-19 Completed Date: 1986-11-19 Revised Date: 2006-08-16 |
Medline Journal Info:
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Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: DENMARK |
Other Details:
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Languages: eng Pagination: 30-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asphyxia Neonatorum
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cerebrospinal fluid,
complications* Brain Damage, Chronic / cerebrospinal fluid*, etiology Follow-Up Studies Humans Infant Infant, Newborn Isoenzymes L-Lactate Dehydrogenase / cerebrospinal fluid* Prognosis |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; EC 1.1.1.27/L-Lactate Dehydrogenase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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