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The LC-MS/MS Methods for the Determination of Specific Antibiotics Residues in Food Matrices.
MedLine Citation:
PMID:  21643914     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
This chapter describes the LC-MS/MS methods for the determination of antibiotics residues in food matrices. The types of antibiotics include β-lactam antibiotics, sulfonamides, tetracyclines, fluoroquinolones, nitrofurans, and chloramphenicol (CAP). The food matrices are mainly from animal origin, such as animal tissues, fishes (marine products), eggs, milk, honey, and so on. The methods and procedures are covered, including three parts: (1) Liquid chromatographic conditions, (2) mass spectrometer conditions, including ionization source, analyzer, and acquisition, and (3) extraction and clean-up methods. In each case, the standard operating procedures (SOPs) for analysis are given with sensitivity, linearity, precision, and recovery. Some criteria of maximum residue limits (MRLs) from the legislation are listed.
Authors:
Gui-Liang Chen; Yan-Yan Fang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  747     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-06-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  309-55     Citation Subset:  IM    
Affiliation:
Shanghai Institute for Food and Drug Control, Shanghai, China, chenguiliang@smda.gov.cn.
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