| L6 myoblast proliferation in response to muscle-derived extracts and serum from exercise-trained rats. | |
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MedLine Citation:
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PMID: 1878977 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum and skeletal muscle-derived extracts (MDE) were bioassayed for their ability to promote [3H]thymidine incorporation in L6 myoblasts to determine if exercise-training increases mitogenic growth factor activity. Rats were trained by climbing a 60 cm vertical grid with progressively greater weight for 7 and 28 days. Serum from 7 day trained rats and vastus MDE from 7 and 28 day trained rats, but not rectus femoris MDE, had increased mitogenic activity compared to serum and MDE from untrained rats. These data suggest that exercise may increase mitogenic growth factors in some skeletal muscles. |
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Authors:
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J A Chromiak; D R Mulvaney; C H Rahe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cell biology international reports Volume: 15 ISSN: 0309-1651 ISO Abbreviation: Cell Biol. Int. Rep. Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1991-10-03 Completed Date: 1991-10-03 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7708050 Medline TA: Cell Biol Int Rep Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 335-44 Citation Subset: IM; S |
Affiliation:
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Interdepartmental Physiology Program, Auburn University, Alabama 36849. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Division Growth Substances / blood, metabolism Hypertrophy Mitogens / blood, metabolism Muscle Development Muscles / cytology*, metabolism Physical Conditioning, Animal Physical Exertion / physiology* Rats Thymidine / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Growth Substances; 0/Mitogens; 50-89-5/Thymidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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