Document Detail

L-usnate-urease interactions: binding sites for polymerization.
MedLine Citation:
PMID:  6223456     Owner:  NLM     Status:  MEDLINE    
L-usnic acid inactivates urease through a process which implicates the blockade of--SH groups in parallel to the formation of inactive polymers. Both L-alanine and L-proline partially reverses the inactivation and effectively diminishes the amount of highly polymerized protein. The amino acids also prevent the linkage of L-usnic acid on the sites of low affinity for the ligand, being then related to the sites of polymerization.
B Cifuentes; I García; C Vicente
Related Documents :
1918036 - Multiple determinants for the high substrate specificity of an angiotensin ii-forming c...
16665346 - A possible role for abscisic acid in regulation of photosynthetic and photorespiratory ...
14580796 - Catabolism of volatile sulfur compounds precursors by brevibacterium linens and geotric...
2902846 - The effect of non-esterified fatty acids on the proton-pumping cytochrome c oxidase rec...
16683126 - Biodegradation of 8-anilino-1-naphthalenesulfonic acid by pseudomonas aeruginosa.
2850726 - Effect of parathyroid hormone on amino acid transport by cultured neonatal mouse calvar...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zeitschrift für Naturforschung. Section C: Biosciences     Volume:  38     ISSN:  0341-0382     ISO Abbreviation:  Z. Naturforsch., C, Biosci.     Publication Date:    1983 Mar-Apr
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2009-06-08    
Medline Journal Info:
Nlm Unique ID:  7801143     Medline TA:  Z Naturforsch C     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  273-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alanine / pharmacology
Proline / pharmacology
Protein Binding
Urease / metabolism*
Reg. No./Substance:
0/Benzofurans; 147-85-3/Proline; 56-41-7/Alanine; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Oral 13-cis-retinoic acid therapy in adenoma sebaceum symmetricum and the most severe forms of acne ...
Next Document:  Diagnosis of the principle cause for sterility in a couple, based on laparoscopic examination