Document Detail

L-usnate-urease interactions: binding sites for polymerization.
MedLine Citation:
PMID:  6223456     Owner:  NLM     Status:  MEDLINE    
L-usnic acid inactivates urease through a process which implicates the blockade of--SH groups in parallel to the formation of inactive polymers. Both L-alanine and L-proline partially reverses the inactivation and effectively diminishes the amount of highly polymerized protein. The amino acids also prevent the linkage of L-usnic acid on the sites of low affinity for the ligand, being then related to the sites of polymerization.
B Cifuentes; I García; C Vicente
Related Documents :
9674016 - Arachidonic acid activates nadph oxidase by a direct, calmodulin-regulated mechanism.
20622436 - The contribution of arabidopsis homologs of l-gulono-1,4-lactone oxidase to the biosynt...
10094636 - D-erythroascorbic acid is an important antioxidant molecule in saccharomyces cerevisiae.
1510716 - Purification and characterization of 3-mercaptolactic acid s-conjugate oxidases.
2219116 - Elevation of individual serum bile acids on exposure to trichloroethylene or alpha-naph...
7512536 - Arachidonic acid metabolism in benign and malignant prostatic tissue in vitro: effects ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Zeitschrift für Naturforschung. Section C: Biosciences     Volume:  38     ISSN:  0341-0382     ISO Abbreviation:  Z. Naturforsch., C, Biosci.     Publication Date:    1983 Mar-Apr
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2009-06-08    
Medline Journal Info:
Nlm Unique ID:  7801143     Medline TA:  Z Naturforsch C     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  273-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alanine / pharmacology
Proline / pharmacology
Protein Binding
Urease / metabolism*
Reg. No./Substance:
0/Benzofurans; 147-85-3/Proline; 56-41-7/Alanine; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Oral 13-cis-retinoic acid therapy in adenoma sebaceum symmetricum and the most severe forms of acne ...
Next Document:  Diagnosis of the principle cause for sterility in a couple, based on laparoscopic examination