Document Detail


L-carnitine supplementation of a soybean-based formula in early infancy: plasma and urine levels of carnitine and acylcarnitines.
MedLine Citation:
PMID:  3351707     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The absence of carnitine in the diet of normal infants results in marked reduction of plasma carnitine levels. In order to evaluate the effects of L-carnitine supplementation of soybean formula, plasma and urine levels of free carnitine and acylcarnitine were compared in infants receiving carnitine-free soybean protein-based formula and the same formula supplemented with 50 and 250 nmol/ml L-carnitine. In infants receiving soybean formula with 50 nmol/ml L-carnitine, the plasma levels of free carnitine were not significantly different from those in infants receiving formula with 250 nmol/ml L-carnitine; however, urine levels of free carnitine were significantly increased when the infants received formula with 250 nmol/ml L-carnitine. In normal full-term infants, supplementation of soybean formula with 50 nmol/ml L-carnitine was sufficient to maintain normal plasma levels that were comparable to breast-fed infants.
Authors:
M Novak; E F Monkus; M Buch; J Silverio; O M Clouston; J C Cassady
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  7     ISSN:  0277-2116     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:    1988 Mar-Apr
Date Detail:
Created Date:  1988-04-22     Completed Date:  1988-04-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  220-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Miami, School of Medicine, Florida 33101.
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MeSH Terms
Descriptor/Qualifier:
Acetylcarnitine / metabolism
Carnitine / metabolism,  therapeutic use*
Humans
Infant
Infant Food*
Soybeans
Chemical
Reg. No./Substance:
14992-62-2/Acetylcarnitine; 541-15-1/Carnitine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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