| L-Theanine reduces psychological and physiological stress responses. | |
| | |
MedLine Citation:
|
PMID: 16930802 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
L-Theanine is an amino acid contained in green tea leaves which is known to block the binding of L-glutamic acid to glutamate receptors in the brain. Because the characteristics of L-Theanine suggest that it may influence psychological and physiological states under stress, the present study examined these possible effects in a laboratory setting using a mental arithmetic task as an acute stressor. Twelve participants underwent four separate trials: one in which they took L-Theanine at the start of an experimental procedure, one in which they took L-Theanine midway, and two control trials in which they either took a placebo or nothing. The experimental sessions were performed by double-blind, and the order of them was counterbalanced. The results showed that L-Theanine intake resulted in a reduction in the heart rate (HR) and salivary immunoglobulin A (s-IgA) responses to an acute stress task relative to the placebo control condition. Moreover, analyses of heart rate variability indicated that the reductions in HR and s-IgA were likely attributable to an attenuation of sympathetic nervous activation. Thus, it was suggested that the oral intake of L-Theanine could cause anti-stress effects via the inhibition of cortical neuron excitation. |
| | |
Authors:
|
Kenta Kimura; Makoto Ozeki; Lekh Raj Juneja; Hideki Ohira |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial Date: 2006-08-22 |
Journal Detail:
|
Title: Biological psychology Volume: 74 ISSN: 0301-0511 ISO Abbreviation: Biol Psychol Publication Date: 2007 Jan |
Date Detail:
|
Created Date: 2006-11-27 Completed Date: 2007-03-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375566 Medline TA: Biol Psychol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 39-45 Citation Subset: IM |
Affiliation:
|
Nagoya University Department of Psychology, Chikusa-ku, Nagoya, 464-8601, Japan. s050308d@mbox.nagoya-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Brain / metabolism Cognition / drug effects Double-Blind Method Electrocardiography Female Glutamates / pharmacology* Glutamic Acid / drug effects, metabolism Heart Rate / drug effects Humans Immunoglobulin A / analysis Male Neural Inhibition / drug effects Psychoneuroimmunology / methods* Receptors, Glutamate / metabolism Saliva / chemistry Stress, Psychological / drug therapy*, immunology* Sympathetic Nervous System / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Glutamates; 0/Immunoglobulin A; 0/Receptors, Glutamate; 3081-61-6/theanine; 56-86-0/Glutamic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Therapeutic hypothermia.
Next Document: Presurgical short term treatment of uterine fibroids with different doses of cetrorelix acetate: a d...