Document Detail


Kynurenic acid content in anti-rheumatic herbs.
MedLine Citation:
PMID:  24364456     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Introduction: The use of herbal medicines is common among people living in rural areas and increasingly popular in urbanized countries. Kynurenic acid (KYNA) is a metabolite of kynurenine possessing anti-inflammatory, anti-oxidative and pain reliving properties. Previous data indicated that the content of KYNA in the synovial fluid of patients with rheumatoid arthritis is lower than in patients with osteoarthritis. Rheumatoid arthritis is a chronic, systemic inflammatory disorder affecting about 1% of the world's population. Aim: The aim of the presented study was to investigate the content of KYNA in 11 herbal preparations used in rheumatic diseases. Materials and methods: The following herbs were studied: bean pericarp, birch leaf, dandelion root, elder flower, horsetail herb, nettle leaf, peppermint leaf and willow bark. An anti-rheumatic mixture of the herbs Reumatefix and Reumaflos tea were also investigated. The herbs were prepared according to producers' directions. In addition, the herbal supplement Devil's Claw containing root of Harpagophytum was used. KYNA content was measured using the high-performance liquid chromatography method, and KYNA was detected fluorometrically. Results: KYNA was found in all studied herbal preparations. The highest content of KYNA was found in peppermint, nettle, birch leaf and the horsetail herb. The lowest content of KYNA was found in willow bark, dandelion root and in the extract from the root of Harpagophytum. Conclusion: These findings indicate that the use of herbal preparations containing a high level of KYNA can be considered as a supplementary measure in rheumatoid arthritis therapy, as well as in rheumatic diseases prevention.
Authors:
Wojciech Zgrajka; Monika Turska; Grażyna Rajtar; Maria Majdan; Jolanta Parada-Turska
Related Documents :
7438426 - Determination of 8-methoxypsoralen in suction-blister fluid and serum by liquid chromat...
22707226 - Novel data analysis tool for semiquantitative lc-ms-ms(2) profiling of n-glycans.
22284876 - Degradation effects in the extraction of antioxidants from birch bark using water at el...
12401366 - Isolation of alpha-1-antitrypsin from human plasma by partitioning in aqueous biphasic ...
23079496 - First example of a lipophilic porphyrin-cardanol hybrid embedded in a cardanol-based mi...
7057386 - Reversed-phase high-pressure liquid chromatographic determination of serum methotrexate...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of agricultural and environmental medicine : AAEM     Volume:  20     ISSN:  1898-2263     ISO Abbreviation:  Ann Agric Environ Med     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9500166     Medline TA:  Ann Agric Environ Med     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  800-2     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  An assessment of health effects of a cardiological prophylaxis programme in a local community with t...
Next Document:  Motor skills, cognitive development and balance functions of children with Down syndrome.