Document Detail


Kraepelin's 'lost biological psychiatry'? Autointoxication, organotherapy and surgery for dementia praecox.
MedLine Citation:
PMID:  18175634     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kraepelin believed that a chronic metabolic autointoxication, perhaps arising from the sex glands, eventually caused chemical damage to the brain and led to the symptoms of dementia praecox. The evolution of Kraepelin's autointoxication theory of dementia praecox is traced through the 5th to 8th (1895 to 1913) editions of his textbook, Psychiatrie. The historical context of autointoxication theory in medicine is explored in depth to enable the understanding of Kraepelin's aetiological assumption and his application of a rational treatment based on it--organotherapy. A brief account of the North American reception of Kraepelin's concept of dementia praecox, its autotoxic basis, and the preferred American style of rational treatment--surgery--concludes the discussion.
Authors:
Richard Noll
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Publication Detail:
Type:  Biography; Historical Article; Journal Article    
Journal Detail:
Title:  History of psychiatry     Volume:  18     ISSN:  0957-154X     ISO Abbreviation:  Hist Psychiatry     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2008-01-07     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013819     Medline TA:  Hist Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  301-20     Citation Subset:  QIS    
Affiliation:
Department of Social Sciences, DeSales University, Center Valley, PA 18034-9568, USA. richard.noll@desales.edu
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MeSH Terms
Descriptor/Qualifier:
Bacterial Infections / complications,  history
Biological Psychiatry / history*
Gastrointestinal Diseases / complications,  history
Germany
History, 19th Century
History, 20th Century
Humans
Organotherapy / history*
Schizophrenia / etiology,  history*,  therapy
Thyroid Diseases / complications,  history
Toxemia / complications,  history*
United States
Personal Name Subject
Personal Name Subject:
Emil Kraepelin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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