| Kounis syndrome secondary to amoxicillin use in an asthmatic patient. | |
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MedLine Citation:
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PMID: 20223532 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A sixty-four year old man with a past history of hypercholesterolemia, asthma, food allergy, epilepsy and myocardial infarction was admitted to the emergency department because of a generalized erythema, nausea, vomiting, and chest pain after taking an oral dose of amoxicillin. Electrocardiography showed ST segment elevation in anterior leads. After coronary angiography, type 2 variant of Kounis syndrome was diagnosed. We present the first case of oral amoxicillin induced Kounis syndrome in an asthmatic patient with severe anaphylactic shock. The present report also shows that atopic people expressing an amplified mast cell degranulation may have more serious hemodynamic decompensation during hypersensitivity reactions. Case selective mast cell surface membrane stabilization should be considered a potential therapeutic strategy for people with food induced allergy, for atopic patients and for patients who have already experienced a first Kounis syndrome. |
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Authors:
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Ana Viana-Tejedor; M Ángeles Espinosa; J Cuesta; A Núñez; H Bueno; F Fernández-Avilés |
Publication Detail:
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Type: Journal Article Date: 2010-03-12 |
Journal Detail:
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Title: International journal of cardiology Volume: 150 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-07-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: e113-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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