| Kounis syndrome: report of 5 cases. | |
| | |
MedLine Citation:
|
PMID: 20461972 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Kounis syndrome has been defined as an acute coronary syndrome that manifests as unstable vasospastic or nonvasospastic angina, and even as acute myocardial infarction. It is triggered by the release of inflammatory mediators following an allergic insult. We report 5 patients attended at our hospital between January 2005 and May 2008 who were diagnosed with unstable angina or acute myocardial infarction-according to analytical parameters, electrocardiographic abnormalities, and/or coronary angiography--in the context of an anaphylactic episode. Age at the time of the episode, age ranged between 50 and 68 years. The results of an allergology study revealed the causal agents to be drugs in 4 cases (nonsteroidal anti-inflammatory drugs and omeprazole) and food in 1 case (kiwi). Coronary disease of a blood vessel was observed in 2 patients. Serious allergic reactions may be the cause of acute coronary syndrome in patients with healthy or altered coronary arteries and no cardiovascular risk factors. |
| | |
Authors:
|
V G?zquez; G Dalmau; P Gaig; C G?mez; S Navarro; J Merc? |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunolog?a Volume: 20 ISSN: 1018-9068 ISO Abbreviation: J Investig Allergol Clin Immunol Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-05-13 Completed Date: 2010-06-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9107858 Medline TA: J Investig Allergol Clin Immunol Country: Spain |
Other Details:
|
Languages: eng Pagination: 162-5 Citation Subset: IM |
Affiliation:
|
Allergology Section, Hospital Universitari de Tarragona Joan XXIII, Tarragona, Tarragona, Spain. vgazquez.hj23.ics@gencat.cat |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Coronary Syndrome
/
complications,
diagnosis*,
physiopathology Aged Anaphylaxis Angina, Unstable Anti-Inflammatory Agents, Non-Steroidal / adverse effects Coronary Angiography Coronary Vasospasm Diagnosis, Differential Drug Hypersensitivity / complications, diagnosis*, physiopathology Electrocardiogram Pattern Female Food Hypersensitivity / complications, diagnosis*, physiopathology Fruit / adverse effects Humans Male Middle Aged Syndrome Troponin I / blood Tryptases / blood |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Troponin I; EC 3.4.21.59/Tryptases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Study of cross-reactivity between proton pump inhibitors.
Next Document: A case of famotidine-induced anaphylaxis.