Document Detail

Kounis syndrome leads to cardiogenic shock.
MedLine Citation:
PMID:  24337242     Owner:  NLM     Status:  In-Data-Review    
Kounis syndrome has been defined as an acute coronary syndrome that manifests as unstable vasospastic or nonvasospastic angina, and even as acute myocardial infarction. It is triggered by the release of inflammatory mediators following an allergic insult or patient ill health, drug intake or environmental exposure. We report on a patient who was admitted to our hospital and diagnosed with unstable angina or acute myocardial infarction - according to analytical parameters, electrocardiographic abnormalities, and/or coronary angiography - in the context of progesterone as inducing factor. The results of a laboratory study revealed electrocardiogram changes, and increased myocardial enzymes, IgE antibodies and eosinophils. The patient experienced recurring chest pain, acute myocardial infarction, and cardiogenic shock after taking progesterone capsules; her medication history of progesterone clearly correlated with the onset of chest pain, which suggested that the cause of the vasospasm may have been related to progesterone use. We did not include patients with a history of bronchial asthma or allergic constitution. Nevertheless, the case suggests there is a correlation between Kounis syndrome and progesterone as inducing factor.
Kuai-Le Chang; Jui Chen; Jun Yu; Xiao-Liang Dou
Publication Detail:
Type:  Journal Article     Date:  2013-10-23
Journal Detail:
Title:  Cardiovascular journal of Africa     Volume:  24     ISSN:  1680-0745     ISO Abbreviation:  Cardiovasc J Afr     Publication Date:    2013 Oct-Nov
Date Detail:
Created Date:  2013-12-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313864     Medline TA:  Cardiovasc J Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  e12-6     Citation Subset:  IM    
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