| KORSAKOFF'S SYNDROME ASSOCIATED WITH ADRENAL VIRILISM. | |
| | |
MedLine Citation:
|
PMID: 14158554 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Korsakoff's syndrome of obscure etiology was observed in a 34-year-old single woman with an 11-year history of hirsutism and mood swings, and previous hospitalizations for mania three years ago and depression 11 years ago.Recently the virilism had intensified with increased muscularity and coarsening of facial features. The 24-hour urinary 17-ketosteroids ranged between 14.4 mg. and 21.5 mg. and were suppressed by dexamethasone. The 17-hydroxycorticosteroid excretion was normal. These and other findings suggested a diagnosis of adrenal virilism due to adrenocortical hyperplasia. In the absence of other discernible causes it appeared that the adrenal pathology was responsible for the Korsakoff's syndrome. Both conditions responded well to glucocorticoid therapy although low doses were necessary to avoid mania.It is speculated that the encephalopathy was due to an associated adrenal insufficiency. Although hypoadrenalism is accepted as a complication of only the infant form of adrenal virilism, it is noteworthy that this patient had pathological pigmentation of her skin. |
| | |
Authors:
|
B A COOKSON |
Related Documents
:
|
10955564 - Waugh's syndrome: a report of six patients. 11180784 - Persistent mullerian duct syndrome associated with transverse testicular ectopia. 22560374 - From stress to functional syndromes: an internist's point of view. 1974834 - Lack of association between dq a and dx a polymorphisms with rheumatoid arthritis and f... 11071114 - Isaacs' syndrome successfully treated by immunoadsorption plasmapheresis. 21647054 - Role of prone ventilation in the management of patients with acute respiratory distress... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Canadian Medical Association journal Volume: 90 ISSN: 0008-4409 ISO Abbreviation: Can Med Assoc J Publication Date: 1964 Jun |
Date Detail:
|
Created Date: 1964-10-01 Completed Date: 1996-12-01 Revised Date: 2011-09-28 |
Medline Journal Info:
|
Nlm Unique ID: 0414110 Medline TA: Can Med Assoc J Country: CANADA |
Other Details:
|
Languages: eng Pagination: 1449-53 Citation Subset: OM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenogenital Syndrome* Amobarbital* Barbiturates* Glutethimide* Hypertrichosis* Korsakoff Syndrome* Phenothiazines* Prednisone* Thioridazine* Trifluoperazine* Virilism* |
| Chemical | |
Reg. No./Substance:
|
0/Barbiturates; 0/Phenothiazines; 117-89-5/Trifluoperazine; 50-52-2/Thioridazine; 53-03-2/Prednisone; 57-43-2/Amobarbital; 77-21-4/Glutethimide |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: TRANSHEPATIC CHOLANGIOGRAPHY.
Next Document: EUSTACHIAN TUBE OBSTRUCTION AND RADIATION THERAPY.