| Korsakoff's syndrome as the initial presentation of multiple sclerosis. | |
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MedLine Citation:
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PMID: 1940990 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 37-year-old man presented with an acute amnestic syndrome of Korsakoff's type and an upper brain-stem oculomotor syndrome. After a moderate improvement with steroid therapy, he developed progressive behavioural changes due to a frontal lobe syndrome, in addition to motor and visual impairment. Memory performance was investigated on several occasions during an 11-year follow-up. Diagnosis of laboratory-supported definite multiple sclerosis was established and magnetic resonance imaging showed disseminated white matter lesions, especially in both medial temporal lobes. No other cause than multiple sclerosis was found for the amnestic syndrome. Among the rare cases of Korsakoff's syndrome in the course of multiple sclerosis, this is to our knowledge the first case in which a memory deficit was the initial manifestation of the disease. |
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Authors:
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A Vighetto; N Charles; M Salzmann; C Confavreux; G Aimard |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of neurology Volume: 238 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 1991 Sep |
Date Detail:
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Created Date: 1991-12-16 Completed Date: 1991-12-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0423161 Medline TA: J Neurol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 351-4 Citation Subset: IM |
Affiliation:
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Clinique de Neurologie, Hôpital Neurologique P. Wertheimer, Lyon, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Amnestic Disorder / etiology* Humans Magnetic Resonance Imaging Male Multiple Sclerosis / complications*, diagnosis Neuropsychological Tests Temporal Lobe / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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