Document Detail


A Koelliker hemoglobin in chick erythrocytes.
MedLine Citation:
PMID:  3665417     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Adult chicken hemoglobins were analysed by ion exchange chromatography and isoelectric focusing and a minor hemoglobin fraction (HbK) was isolated. 2. Analysis of the constituent chains shows that HbK differs from the two major hemoglobins HbA and HbD in the alpha globin. 3. The amino acid composition, the tryptic peptide maps, the results of carboxypeptidase digestion and the functional properties show that the HbK alpha globin is quite similar to that of HbA except that the C-terminal amino acid Arg 141 is lacking. 4. HbK must then be considered a Koelliker-type hemoglobin.
Authors:
C Cirotto; A Parente
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. B, Comparative biochemistry     Volume:  87     ISSN:  0305-0491     ISO Abbreviation:  Comp. Biochem. Physiol., B     Publication Date:  1987  
Date Detail:
Created Date:  1987-12-02     Completed Date:  1987-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984730R     Medline TA:  Comp Biochem Physiol B     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1025-32     Citation Subset:  IM    
Affiliation:
Istituto di Biologia Cellulare, Perugia, Italy.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis
Animals
Carboxypeptidases
Carboxypeptidases A
Chickens / blood*
Erythrocytes / analysis*
Hemoglobin A / isolation & purification
Hemoglobins, Abnormal / isolation & purification*,  metabolism
Macromolecular Substances
Oxyhemoglobins / metabolism
Peptide Mapping
Trypsin
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Hemoglobins, Abnormal; 0/Macromolecular Substances; 0/Oxyhemoglobins; 0/hemoglobin Koelliker; 39346-78-6/hemoglobin D; 9034-51-9/Hemoglobin A; EC 3.4.-/Carboxypeptidases; EC 3.4.17.1/Carboxypeptidases A; EC 3.4.21.4/Trypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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