Document Detail


Kodamaea ohmeri as an emerging pathogen: a case report and review of the literature.
MedLine Citation:
PMID:  21438792     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kodamaea (Pichia) ohmeri is a yeast-like fungus that has recently emerged as an important etiologic agent of fungemia in immunocompromised patients. We report such a case in a premature neonate born at 29 weeks of gestation. Prior to developing fungemia, she had two episodes of bacterial sepsis on day 13 and day 32 due to Enterobacter cloacae and Staphylococcus epidermidis, respectively. Kodamaea ohmeri was repeatedly isolated from blood cultures and its identity was determined by phenotypic characteristics and sequencing of the ITS and D1/D2 regions of rDNA. The neonate was successfully treated with amphotericin B. The published cases of K. ohmeri fungemia reported in pediatric patients are reviewed highlighting its increasing importance as a bloodstream pathogen.
Authors:
Noura Al-Sweih; Zia U Khan; Suhail Ahmad; Laxmi Devarajan; Seema Khan; Leena Joseph; Rachel Chandy
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2011-03-28
Journal Detail:
Title:  Medical mycology     Volume:  49     ISSN:  1460-2709     ISO Abbreviation:  Med. Mycol.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-09-06     Completed Date:  2012-01-10     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  9815835     Medline TA:  Med Mycol     Country:  England    
Other Details:
Languages:  eng     Pagination:  766-70     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amphotericin B / administration & dosage
Antifungal Agents / administration & dosage
Bacteremia / complications,  diagnosis,  microbiology
Communicable Diseases, Emerging / diagnosis*,  epidemiology,  microbiology*
DNA, Fungal / chemistry,  genetics
DNA, Ribosomal / chemistry,  genetics
DNA, Ribosomal Spacer / chemistry,  genetics
Enterobacter cloacae / isolation & purification
Female
Fungemia / diagnosis*,  epidemiology,  microbiology*
Humans
Infant, Newborn
Microbial Sensitivity Tests
Molecular Sequence Data
Mycological Typing Techniques
Phylogeny
Saccharomycetales / isolation & purification*
Sequence Analysis, DNA
Staphylococcus epidermidis / isolation & purification
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/DNA, Fungal; 0/DNA, Ribosomal; 0/DNA, Ribosomal Spacer; 7XU7A7DROE/Amphotericin B

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