Document Detail

Knowledge generating in expert systems as support of immunological investigations.
MedLine Citation:
PMID:  10179745     Owner:  NLM     Status:  MEDLINE    
One of the most important parameters in immunologic investigations linked with the analysis of TIL phenotypic characteristics is the ratio between particular populations and subpopulations of TIL. Values of exact parameter are not obtained with its direct measurement but with indirect measurement of values in its numerator and its denominator that represent mean values of absolute TIL figures. Exactness of estimate of specific parameter is obtained by determining the intervals of values where this parameter should lie. Determination of confidence intervals for relationship between particular populations and subpopulations of TIL was performed using Fieller's theorem which full filled requests from the nature and process of obtaining exact parameter. By analyzing the obtained confidence intervals informations can be obtained regarding TIL phenotypic characteristics of various histologic types of tumors and various types of intervals within, as well as changes in TIL content that are occurring in malignant tumors.
M Biljana; M Jelena; R Milorad; J Branislav; A Nebojsa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Studies in health technology and informatics     Volume:  43 Pt B     ISSN:  0926-9630     ISO Abbreviation:  Stud Health Technol Inform     Publication Date:  1997  
Date Detail:
Created Date:  1998-06-30     Completed Date:  1998-06-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9214582     Medline TA:  Stud Health Technol Inform     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  642-6     Citation Subset:  T    
Department of Statistics, Medical Faculty, Kragujevac, Yugoslavia.
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MeSH Terms
Artificial Intelligence*
Confidence Intervals
Diagnosis, Computer-Assisted*
Expert Systems*
Fluorescent Antibody Technique, Indirect
Lymphocytes, Tumor-Infiltrating / immunology*
Neoplasms / diagnosis,  immunology*

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