Document Detail


Knowledge of alpha-1 antitrypsin deficiency among internal medicine house officers and respiratory therapists: results of a survey.
MedLine Citation:
PMID:  20196882     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Alpha-1 antitrypsin deficiency is a common genetic condition that predisposes to emphysema and liver disease. Alpha-1 antitrypsin deficiency is under-recognized, so affected individuals often experience long delays in diagnosis and visits to multiple physicians before correct diagnosis. Reasoning that inadequate knowledge about alpha-1 antitrypsin deficiency could contribute to this under-recognition, we designed this study to evaluate internal medicine house officers' and respiratory therapists' (RTs) knowledge of alpha-1 antitrypsin deficiency. METHODS: We evaluated knowledge of alpha-1 antitrypsin deficiency with a Web-based test containing 30 multiple-choice questions. Invitations to take the test were sent via e-mail to all internal medicine house officers and RTs at The Cleveland Clinic main campus hospital. We assessed test scores by profession, years of training/experience, and self-assessed knowledge of alpha-1 antitrypsin deficiency. RESULTS: Of 332 invitees, 202 (61%) responded, of whom 165 (50%) provided complete responses (99 RTs, 66 physicians). The mean scores (percent of correct answers) were 54% and 52% for physicians and RTs, respectively (P = .25). The scores did not differ among the physicians when examined by subspecialty (pulmonary/critical care vs other) or post-graduate education level (P = .94). RTs who had graduated from a 4-year respiratory therapy program had a higher mean score than those who had graduated from a 2-year program (56% vs 50%, P = .02). Respondents' whose self-assessment of their knowledge about alpha-1 antitrypsin deficiency was "somewhat knowledgeable" had higher test scores than any other self-assessed knowledge level, regardless of profession. CONCLUSIONS: These results indicate a generally low level of knowledge about alpha-1 antitrypsin deficiency among physicians and RTs. Causes of under-recognition of alpha-1 antitrypsin deficiency, including the possibility of poor knowledge as a contributor, warrant further study.
Authors:
Rachel M Taliercio; Robert L Chatburn; James K Stoller
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Respiratory care     Volume:  55     ISSN:  0020-1324     ISO Abbreviation:  Respir Care     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-03     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  322-7     Citation Subset:  IM    
Affiliation:
Department of Pulmonary, Allergy, and Critical Care Medicine, Respiratory Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA.
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MeSH Terms
Descriptor/Qualifier:
Clinical Competence*
Humans
Internal Medicine*
Internship and Residency
Questionnaires
Respiratory Therapy*
alpha 1-Antitrypsin Deficiency* / diagnosis,  epidemiology,  genetics,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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