Document Detail

Knowledge and willingness to provide research biospecimens among foreign-born Latinos using safety-net clinics.
MedLine Citation:
PMID:  23543371     Owner:  NLM     Status:  MEDLINE    
Latinos tend to be under-represented in cancer research and in bio-repositories. We conducted a Spanish-language, interviewer-administered cross-sectional survey of 331 foreign-born Latinos from Central and South America attending safety-net clinics in order to describe factors associated with knowledge about and intention to provide bio-specimens for research purposes. We used logistic regression and multiple imputation methods to evaluate associations between socio-cultural measures, medical trust, demographics, as well as knowledge about and intentions to provide bio-specimens. Almost half (47 %) of respondents knew what bio-specimens were, and 67 % said that they would provide a specimen after being given information about what this involved; this increased to 72 % among those with prior knowledge. Controlling for covariates, Latinos with a high school education and above were more likely to know what a bio-specimen was and to say they would provide bio-specimens than were those with lower levels of education [adjusted OR (aOR) 2.85, 95 % CI 1.37-5.96; and 3.49, 95 % CI 1.41-8.63, p ≤ 0.01, respectively]. Those with greater social integration were more likely to know about bio-specimens than those with less integration (aOR 2.54, 95 % CI 1.45-4.46, p = 0.001). Higher endorsement of family values was independently associated with intent to give bio-specimens (aOR 1.11, 95 % CI 1.02-1.20, p = 0.017 per five-point increase in "familism" score). Medical mistrust was not related to intentions to provide specimens. Our results suggest that interventions to increase willingness to provide bio-specimens could leverage trusted clinics or social networks and should consider individuals' education and socio-cultural perspectives.
Christopher A Loffredo; Gheorghe Luta; Sherrie Wallington; Solomon B Makgoeng; Claire Selsky; Jeanne S Mandelblatt; Lucile L Adams-Campbell;
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of community health     Volume:  38     ISSN:  1573-3610     ISO Abbreviation:  J Community Health     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-08     Completed Date:  2014-04-03     Revised Date:  2014-08-04    
Medline Journal Info:
Nlm Unique ID:  7600747     Medline TA:  J Community Health     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  652-9     Citation Subset:  IM    
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MeSH Terms
Attitude to Health
Biomedical Research*
Cross-Sectional Studies
Emigrants and Immigrants / psychology*
Health Knowledge, Attitudes, Practice*
Hispanic Americans / psychology*
Safety-net Providers / statistics & numerical data*
Socioeconomic Factors
Specimen Handling / psychology
Grant Support
2K05CA096940/CA/NCI NIH HHS; 3P30CA051008-17S3/CA/NCI NIH HHS; K01 CA155417/CA/NCI NIH HHS; K05 CA096940/CA/NCI NIH HHS; P30 CA051008/CA/NCI NIH HHS; P30CA51008/CA/NCI NIH HHS; U01 CA114593/CA/NCI NIH HHS; U01 CA114593/CA/NCI NIH HHS
Lucile Adams-Campbell / ; Shereida Muthra / ; Sarah Reisinger / ; Peter Shields /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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