Document Detail

Knee laxity after staircase exercise predicts radiographic disease progression in medial compartment knee osteoarthritis.
MedLine Citation:
PMID:  22886496     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate whether the increased laxity of the knee during daily physical activities such as stair climbing is associated with progression of knee joint OA. METHODS: During 2001-2003, 136 patients with primary bilateral medial compartment knee joint OA managed at our Orthopaedic Unit were enrolled in this prospective study. Baseline data collected were BMI, muscle power, radiographic joint space width, mechanical axis on a standing radiograph, and antero-posterior (A-P) knee laxity before and after physical exercise. At 8-year follow-up, 84 patients were re-examined to assess radiographic changes. Radiographic disease progression was defined as more than one grade progression on the Kellgren and Lawrence scale. RESULTS: A-P knee laxity increased significantly after staircase climbing. Patients with OA progression and without progression did not differ significantly in age, gender, baseline quadriceps muscle strength, mechanical axis, joint space width, and A-P knee laxity before exercise. The two groups of patients did however differ significantly in baseline BMI and change in A-P knee laxity due to exercise. The risk of progression of knee OA increased 4.15 times with each extra mm of changes in A-P knee laxity due to exercise, and 1.24 times with each point increases in BMI. CONCLUSIONS: Our results indicate that patients with OA progression have significantly larger changes in knee joint laxity during physical activities and a larger BMI than patients without OA progression. Our results suggest larger changes in knee laxity during repetitive physical activities and a higher BMI play a significant role in the progression of knee OA. (251 words).
Tsuyoshi Miyazaki; Kenzo Uchida; Mitsuhiko Sato; Shuji Watanabe; Ai Yoshida; Makoto Wada; Seiichiro Shimada; Jan Herman Kuiper; Hisatoshi Baba
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-8
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  -     ISSN:  1529-0131     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 by the American College of Rheumatology.
Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
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