Document Detail

Knee joint synovitis in Behçet's disease: a sonographic study.
MedLine Citation:
PMID:  17949556     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to investigate, using ultrasound (US), knee involvement in patients with Behçet's disease (BD). METHODS: Knee US was performed in 30 unselected Italian BD patients. Signs of arthritis (joint effusion, synovial proliferation) and presence of bone erosions and Baker's cysts were recorded. Power Doppler evaluation was performed. A semi-quantitative score was used for each structure examined, whereby 0 was to indicate the absence of any change and score from 1 to 3 the presence of mild to severe changes. A sum of the single scores was obtained. Disease activity was evaluated to identify the correlation with the US modifications. RESULTS: Twenty (66.6%) patients had symptomatic articular involvement and US showed knee involvement in 18 of them (60%). Synovial proliferation was detected in 14 (46%, positive power Doppler in 4), joint effusion in 14 (46%), bone surface erosions in 3 (10%). Four patients, asymptomatic for joint involvement, showed US alterations. Eleven patients showed a total score between 1 and 3, while the other 7 had a score between 4 and 6. Subjects with a higher US score presented an increased prevalence of acneiform skin lesions with respect to the group with US score 1-3. Statistical analysis showed a positive correlation between disease activity and US score in group 2 (p=0.04). CONCLUSION: This study confirms that peripheral joint involvement represents an important clinical aspect in italian BD patients and US evaluation is useful for the detection of this aspect.
F Ceccarelli; R Priori; A Iagnocco; G Coari; M Accorinti; P Pivetti Pezzi; G Valesini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  25     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-10-22     Completed Date:  2008-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  S76-9     Citation Subset:  IM    
Divisione e Cattedra di Reumatologia, Dipartimento di Scienze Oftalmiche, Università "La Sapienza", Roma, Italy.
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MeSH Terms
Arthritis / ultrasonography
Behcet Syndrome / pathology*
Cohort Studies
Knee Joint / pathology*,  ultrasonography
Middle Aged
Severity of Illness Index
Synovial Fluid / ultrasonography
Synovitis / pathology*,  ultrasonography

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