Document Detail

Kluver-Bucy syndrome--a rare complication of herpes simplex encephalitis.
MedLine Citation:
PMID:  17444064     Owner:  NLM     Status:  MEDLINE    
A twelve-year-old female was admitted with history of high fever, recurrent vomiting and repeated convulsion for 2 days and altered consciousness for one day. Cranial CT scan showed intraparenchymal haemorrhage involving both temporal lobes and right basal ganglia region without mass effect. Serology was reactive against IGM HSV1. Injection acyclovir was started at a dose of 10 mg/kg 8 hourly intravenously. Patient regained consciousness on fourth day but speech was altered. Abnormal behavioural symptoms were noticed. EEG showed generalised spike and slow waves and sharp and slow wave discharge more in the temporal region. The patient was given clonidine and carbamazepine. She also received behavioural therapy and parental counselling. She was followed up for six months and maintaining well.
Hosenara Begum; Kaustav Nayek; Bidyut Kr Khuntdar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the Indian Medical Association     Volume:  104     ISSN:  0019-5847     ISO Abbreviation:  J Indian Med Assoc     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505608     Medline TA:  J Indian Med Assoc     Country:  India    
Other Details:
Languages:  eng     Pagination:  637-8     Citation Subset:  IM    
Department of Paediatrics, Medical College, Kolkata.
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MeSH Terms
Acyclovir / therapeutic use
Antiviral Agents / therapeutic use
Carbamazepine / therapeutic use
Clonidine / therapeutic use
Encephalitis, Herpes Simplex / complications*
Kluver-Bucy Syndrome / drug therapy,  etiology*
Risk Factors
Reg. No./Substance:
0/Antiviral Agents; 298-46-4/Carbamazepine; 4205-90-7/Clonidine; 59277-89-3/Acyclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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