Document Detail

Klippel-Trenaunay-type syndrome in pregnancy.
MedLine Citation:
PMID:  16490119     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Klippel-Trenaunay-Type Syndrome (KTTS) is a rare congenital anomaly with variable expression and an unknown etiology characterized by capillary and venous malformations and hypertrophy of bone and soft tissue. Pregnancy has been rarely reported in patients with KTTS and since 1989 there have been only 13 case reports of pregnancy in women with KTTS reported in the literature. Concurrent pregnancy is associated with adverse perinatal outcomes. To the best of our knowledge this is the second reported, and largest, series of cases. STUDY DESIGN: After a thorough review of the literature, the medical records of four obstetrical patients with KTTS were reviewed. RESULTS: The obstetrical course of women with KTTS varies. Complications include bleeding, DIC, thromboembolic events, and pain. CONCLUSIONS: The maternal and fetal risks associated with pregnancy in women with KTTS are proportional to the severity of disease, which can be exacerbated by pregnancy. Thoughtful preconceptional counseling, along with methodical and systematic intrapartum and postpartum care are keys to reducing mortality and morbidity.
Susan R Stein; Jordan H Perlow; Shirley K Sawai
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Obstetrical & gynecological survey     Volume:  61     ISSN:  0029-7828     ISO Abbreviation:  Obstet Gynecol Surv     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-21     Completed Date:  2006-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401007     Medline TA:  Obstet Gynecol Surv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  194-206     Citation Subset:  IM    
Department of Obstetrics & Gynecology, Banner Good Samaritan Medical Center, Phoenix, Arizona 85006, USA.
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MeSH Terms
Anticoagulants / therapeutic use
Education, Medical, Continuing
Fetal Development*
Klippel-Trenaunay-Weber Syndrome / complications*
Pregnancy Complications, Hematologic*
Pregnancy Outcome
Severity of Illness Index
Reg. No./Substance:

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