Document Detail


Kleine-Levin syndrome in a 14-year-old girl: CSF hypocretin-1 measurements.
MedLine Citation:
PMID:  17098473     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CSF hypocretin-1 measurements were performed during a period of hypersomnia and during an asymptomatic interval in a 14-year-old girl affected with severe Kleine-Levin syndrome. A twofold decrease in hypocretin-1 was evidenced during the period of hypersomnia in comparison with the asymptomatic interval. Together with previous data, this result is in favour of recurrent dysfunction at the hypothalamic level in Kleine-Levin syndrome.
Authors:
Claudio Podestá; Mónica Ferreras; Marcela Mozzi; Claudio Bassetti; Yves Dauvilliers; Michel Billiard
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-11-13
Journal Detail:
Title:  Sleep medicine     Volume:  7     ISSN:  1389-9457     ISO Abbreviation:  Sleep Med.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-03-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898759     Medline TA:  Sleep Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  649-51     Citation Subset:  IM    
Affiliation:
Department of Neurology FLENI, Sleep Laboratory, Buenos-Aires, Argentina. cpodesta@fleni.org.ar
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Female
Humans
Hypothalamus / physiopathology
Intracellular Signaling Peptides and Proteins / cerebrospinal fluid*
Kleine-Levin Syndrome / cerebrospinal fluid*
Neuropeptides / cerebrospinal fluid*
Chemical
Reg. No./Substance:
0/Intracellular Signaling Peptides and Proteins; 0/Neuropeptides; 0/orexins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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