Document Detail

Kleine-Levin syndrome. Clinical course, polysomnography and multiple sleep latency test. Case report.
MedLine Citation:
PMID:  9850764     Owner:  NLM     Status:  MEDLINE    
A case of Kleine-Levin syndrome, with chronic severe periodic hypersomnia is described in a 17-year-old female. The first episode started when she was 15 years old. The episodes were characterized by periodic hypersomnia accompanied by hyperphagia, lasting 5 days, and repeating at 28 to 60 day intervals. The severity of hypersomnia prevented her from attending school activities. Outside the hypersomnia periods, she was asymptomatic. EEG, brain computerized tomography and brain nuclear magnetic resonance were normal; all-night polysomnography, Multiple Sleep Latency Test (MSLT) and Epworth Sleepiness Scale (ESS) were within normal limits. During the period of hypersomnolence, polysomnography showed short sleep latency and short REM latency. MSLT mean sleep latency was 1.8 min; and REM period was present in one subtest; the ESS was markedly elevated.
R Reimão; M H Shimizu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  56     ISSN:  0004-282X     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1999-03-16     Completed Date:  1999-03-16     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  BRAZIL    
Other Details:
Languages:  eng     Pagination:  650-4     Citation Subset:  IM    
CDS-Centro de Distúrbios do Sono, São Paulo, Brasil.
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MeSH Terms
Carbamazepine / therapeutic use
Kleine-Levin Syndrome / diagnosis*,  drug therapy
Reaction Time / physiology
Reg. No./Substance:

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