Document Detail


Kissing selectively decreases allergen-specific IgE production in atopic patients.
MedLine Citation:
PMID:  16650596     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Stress enhanced allergic skin wheal responses and allergen-specific IgE production. In contrast, mothers' kissing caused relaxation in infants, and kissing by lovers or spouses to atopic patients reduced allergic skin wheal responses. I studied the effect of kissing on production of allergen-specific IgE and cytokines in atopic patients. METHODS: Twenty-four patients with mild atopic eczema and 24 patients with mild allergic rhinitis kissed with lovers or spouses freely for 30 min while listening to soft music. Just before and immediately after kissing, blood mononuclear cells were separated cultured for allergen, and production of allergen-specific immunoglobulin and cytokine was measured. RESULTS: Kissing selectively decreased allergen-specific IgE production with skewing cytokine pattern toward Th1 type. CONCLUSION: Kissing may alleviate allergic symptoms by decrease in allergen-specific IgE production.
Authors:
H Kimata
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychosomatic research     Volume:  60     ISSN:  0022-3999     ISO Abbreviation:  J Psychosom Res     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-02     Completed Date:  2006-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376333     Medline TA:  J Psychosom Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  545-7     Citation Subset:  IM    
Affiliation:
Department of Allergy, Satou Hospital, 65-1 Yabuhigashimachi, Hirakata-City, Osaka Prefecture 573-1124, Japan. kimata@misugikai.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibody Formation / immunology*
Choice Behavior*
Cytokines / immunology
Dermatitis, Atopic / epidemiology*,  immunology*
Female
Humans
Immunoglobulin E / immunology*
Interpersonal Relations*
Love*
Male
Sexual Partners*
Chemical
Reg. No./Substance:
0/Cytokines; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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