Document Detail


King's syndrome with malignant hyperthermia. Potential outpatient risks.
MedLine Citation:
PMID:  3812408     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
King's syndrome is a sporadic genetic syndrome exhibiting characteristic facial features, short stature, and subclinical myopathy. Affected individuals are susceptible to malignant hyperthermia (MH) induced by anesthesia, stress, or trauma. The incidence of King's syndrome is uncertain as all reported cases were first recognized following an episode of MH. We report a case of King's syndrome without the cryptorchidism and pectus carinatum associated with the syndrome. King's syndrome's possible link to Noonan's syndrome is discussed herein, and the diagnosis and management of MH are briefly reviewed. We recommend evaluation for MH susceptibility in all patients with clinical signs consistent with King's syndrome and in their family members prior to anesthesia.
Authors:
A J Steenson; R D Torkelson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  141     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-03-26     Completed Date:  1987-03-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  271-3     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / complications*
Adolescent
Anesthesia, General / adverse effects
Diseases in Twins
Facial Bones / abnormalities
Growth Disorders / complications
Humans
Male
Malignant Hyperthermia / complications*
Muscular Diseases / complications
Risk
Succinylcholine / adverse effects
Syndrome
Chemical
Reg. No./Substance:
306-40-1/Succinylcholine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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