Document Detail

Kinetics of specific food intake and weight gain in rat.
MedLine Citation:
PMID:  7137384     Owner:  NLM     Status:  MEDLINE    
We report the expanded application of a recently developed time-invariant analytic function that relates food intake, growth (weight gain), and dietary nutrient concentration in the laboratory rat. Data from seven experiments were utilized, providing analysis of three stages of rat (Sprague-Dawley) growth (weanling, adult, and pregnant) and a variety of nutrients: casein, lactalbumin, amino acid mix, thiamin, and pyridoxine. For each experiment the rats were fed graded levels of a nutrient, ranging from 0% to a percentage well above the recommended amount, in an otherwise nutritionally adequate diet. Weight-specific weight gains and food intakes were calculated for each dietary group and fitted to the Gompertz equation. The resulting rate constants for each group were identical for weight gain and food intake. The rate constants were then fitted as functions of dietary nutrient concentration by the four-parameter mathematical model for physiological responses. Kinetic rate constants could be characterized as functions of the dietary concentration of each nutrient tested. This approach offers new possibilities for the determination and optimization of dietary requirements. With this approach, one may characterize food intake and growth in a single rate constant, which varies as a function of dietary nutrient concentration.
S S Burkhardt; L P Mercer; M R Schweisthal; T B Cole
Related Documents :
10410844 - Nutrient requirements at high altitude.
10093274 - Preliminary assessment of nutrients in daily diets of a sample of belcher island inuit ...
8860794 - Dietary intakes of adolescent females consuming vegetarian, semi-vegetarian, and omnivo...
11125974 - Dietary guidelines in the czech republic. ii.: nutritional profiles of food groups.
24934554 - Antimicrobial and p450 inhibitory properties of common functional foods.
23142564 - Healthy dining: subtle diet reminders at the point of purchase increase low-calorie foo...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of physiology     Volume:  243     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1982 Nov 
Date Detail:
Created Date:  1982-12-18     Completed Date:  1982-12-18     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  R531-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Body Weight*
Rats, Inbred Strains
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effects of aldosterone on potassium distribution.
Next Document:  Role of central and peripheral chemoreceptors in diving responses of ducks.