| Kinetics of procalcitonin in cardiogenic shock and in septic shock. Preliminary data. | |
| | |
MedLine Citation:
|
PMID: 20698733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: In cardiac acute patients, data on procalcitonin (PCT) are controversial and the clinical interpretation of absolute PCT values represents a major challenge since they may be influenced by several factors. No data are so far available on the dynamics of PCT levels in patients with cardiogenic shock. AIMS: to evaluate the serum evolution of PCT during intensive cardiac care unit (ICCU) staying in a group of 24 patients with cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI) submitted to primary percutaneous intervention (PCI) with no laboratory or clinical sign of infection. Furthermore we assessed the kinetics of PCT in a series of 24 patients with septic shock. RESULTS: In septic shock, no significant difference was detectable in PCT kinetics between survivors (R2 = 0.90; P = 0.051) and non-survivors (R2 = 0.63; P = 0.204). In cardiogenic shock, survivors exhibited a significant reduction in PCT values (R2 = 0.94; P = 0.032) while non survivors did not (R2 = 0.68; P = 0.178). CONCLUSIONS: differently from septic shock, cardiogenic shock following STEMI was associated with heterogeneous patterns of temporal PCT variations since only patients who survived exhibited a significant PCT reduction during ICCU stay. Our findings support the contention that the 'dynamic' approach may be more reliable that the static one especially in cardiogenic shock. |
| | |
Authors:
|
Claudio Picariello; Chiara Lazzeri; Serafina Valente; Marco Chiostri; Paola Attanà; Gian Franco Gensini |
Related Documents
:
|
10660963 - Primary coronary angioplasty in acute myocardial infarction excluded from thrombolysis:... 19077633 - Esophageal echo-doppler monitoring in burn shock resuscitation: are hemodynamic variabl... 12662213 - Effects of direct mechanical ventricular assistance on regional myocardial function in ... |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Acute cardiac care Volume: 12 ISSN: 1748-295X ISO Abbreviation: Acute Card Care Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-02 Completed Date: 2010-11-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101276603 Medline TA: Acute Card Care Country: England |
Other Details:
|
Languages: eng Pagination: 96-101 Citation Subset: IM |
Affiliation:
|
Intensive Cardiac Care Unit, Heart and Vessel Department, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy. claudx@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Biological Markers C-Reactive Protein / metabolism Calcitonin / blood* Electrocardiogram Pattern Female Humans Intensive Care Units Male Middle Aged Myocardial Infarction / blood*, complications, mortality, therapy Protein Precursors / blood* Shock, Cardiogenic / blood*, diagnosis*, etiology Shock, Septic / blood*, diagnosis* Survival Analysis |
| Chemical | |
Reg. No./Substance:
|
0/Biological Markers; 0/Protein Precursors; 56645-65-9/procalcitonin; 9007-12-9/Calcitonin; 9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prevention and treatment of no-reflow.
Next Document: The relationship between hypertension and salt intake in Turkish population: SALTURK study.