| Kinetics of maternal antibodies against rubella and varicella in infants. | |
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MedLine Citation:
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PMID: 20558248 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Kinetics of maternal rubella and varicella antibodies in 213 mother-infant pairs are described in a longitudinal study in Belgium. Blood samples are taken at 7 time points (week 36 of pregnancy, birth (cord), 1, 3, 6, 9, and 12 months), and analyzed for anti-rubella IgG and anti-varicella IgG by enzyme linked immunosorbent assay (ELISA). A generalized exponential model is used to analyse maternal antibody decay in infants. Model based, the mean duration of passive immunity is 2.1 months for rubella and 2.4 months for varicella. Infants are susceptible at young age for rubella, a disease with high vaccination coverage, as well as for varicella, an endemic disease in Western Europe. |
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Authors:
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E Leuridan; N Hens; V Hutse; M Aerts; P Van Damme |
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Publication Detail:
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Type: Journal Article Date: 2010-06-15 |
Journal Detail:
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Title: Vaccine Volume: 29 ISSN: 1873-2518 ISO Abbreviation: Vaccine Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8406899 Medline TA: Vaccine Country: Netherlands |
Other Details:
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Languages: eng Pagination: 2222-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, Faculty of Medicine, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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