Document Detail

Kinetics of estimated human muscle capillary blood flow during recovery from exercise.
MedLine Citation:
PMID:  15908509     Owner:  NLM     Status:  MEDLINE    
The kinetic characteristics of muscle capillary blood flow (Qcap) during recovery from exercise are controversial (e.g. one versus two phases). Furthermore, it is not clear how the overall Qcap kinetics are temporally associated with muscle oxygen uptake (VO2m) kinetics. To address these issues, we examined the kinetics of Qcap estimated from the rearrangement of the Fick equation (Qcap=VO2m/C(a-v)O2) using the kinetics of pulmonary VO2 (VO2p, primary component) and deoxy-haemoglobin concentration ([HHb]) as indices of VO2m and C(a - v)O2 (arterio-venous oxygen difference) kinetics, respectively. VO2p (l min-1) was measured breath by breath and [HHb] (microm) was measured by near infrared spectroscopy during moderate (M; below lactate threshold, LT) and heavy exercise (H, above LT) in nine subjects. The kinetics of Qcap were biphasic, with an initial fast phase (tauI; M=9.3+/-4.9 s and H=6.0+/-3.8 s) followed by a slower phase 2 (tauP; M=29.9+/-8.6 s and H=47.7+/-26.0 s). For moderate exercise, the overall kinetics of Qcap (mean response time [MRT], 36.1+/-8.6 s) were significantly slower than the kinetics of VO2p (tauP; 27.8+/-5.3 s) and [HHb] (MRT for [HHb]; 16.2+/-6.3 s). However, for heavy exercise, there was no significant difference between MRT-[HHb] (34.7+/-10.4 s) and tauP for VO2p (32.3+/-6.7 s), while MRT for Qcap (48.7+/-21.8 s) was significantly slower than MRT for [HHb] and tauP for VO2p. In conclusion, during recovery from exercise the estimated Qcap kinetics were biphasic, showing an early rapid decrease in blood flow. In addition, the overall kinetics of Qcap were slower than the estimated VO2m kinetics.
Leonardo F Ferreira; Allison J Harper; Dana K Townsend; Barbara J Lutjemeier; Thomas J Barstow
Related Documents :
9644039 - Delayed vagal withdrawal slows circulatory but not oxygen uptake responses at work incr...
7657419 - The metabolic cost of two kayaking techniques.
16540709 - Exercise training in normobaric hypoxia in endurance runners. i. improvement in aerobic...
487269 - Alterations in ventilation and gas exchange during exercise-induced carbohydrate deplet...
16203049 - Postexercise vo2 "hump" phenomenon as an indicator for inducible myocardial ischemia in...
8435979 - High anaerobic energy release during submaximal arm exercise.
15851289 - Long-term changes in sequence of atrial activation and refractory periods: no evidence ...
19000099 - Mouth rinse but not ingestion of a carbohydrate solution improves 1-h cycle time trial ...
2632139 - Computer linked apparatus for upper limb therapy: a new system of resistive exercise.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-05-20
Journal Detail:
Title:  Experimental physiology     Volume:  90     ISSN:  0958-0670     ISO Abbreviation:  Exp. Physiol.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-22     Completed Date:  2005-11-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  715-26     Citation Subset:  IM    
Department of Anatomy and Physiology, Kansas State University, Manhattan, KA 66506-0302, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Flow Velocity
Capillaries / physiology*
Exercise / physiology*
Exercise Test
Hemoglobins / metabolism
Muscle, Skeletal / blood supply*
Oxygen Consumption / physiology
Regional Blood Flow*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Anoxia induces Ca2+ influx and loss of cell membrane integrity in rat extensor digitorum longus musc...
Next Document:  Resting and evoked spinal substance P release during chronic intrathecal morphine infusion: parallel...