Document Detail

Kinetics of Physiological Skin Flora in a Suction Blister Wound Model on Healthy Subjects after Treatment with Water-Filtered Infrared-A Radiation.
MedLine Citation:
PMID:  22123525     Owner:  NLM     Status:  Publisher    
The effect of water-filtered infrared-A radiation (wIRA) on normal skin flora was investigated by generating experimental wounds on the forearms of volunteers utilizing the suction blister technique. Over 7 days, recolonization was monitored parallel to wound healing. Four groups of treatment were compared: no therapy (A), dexpanthenol cream once daily (B), 20 min wIRA irradiation at 30 cm distance (C), and wIRA irradiation for 30 min once daily together with dexpanthenol cream once daily (D). All treatments strongly inhibited the recolonization of the wounds. Whereas dexpanthenol completely suppressed recolonization over the test period, recolonization after wIRA without (C) and in combination with dexpanthenol (D) was suppressed, but started on day 5 with considerably higher amounts after the combination treatment (D). Whereas the consequence without treatment (A) was an increasing amount of physiological skin flora including coagulase-negative staphylococci, all treatments (B-D) led to a reduction in physiological skin flora, including coagulase-negative staphylococci. In healthy volunteers, wIRA alone and in combination with dexpanthenol strongly inhibited bacterial recolonization with physiological skin flora after artificial wound setting using a suction-blister wound model. This could support the beneficial effects of wIRA in the promotion of wound healing.
G Daeschlein; J Alborova; A Patzelt; A Kramer; J Lademann
Related Documents :
25182865 - The efficacy of risk scores for predicting abdominal wound dehiscence: a case-controlle...
22123525 - Kinetics of physiological skin flora in a suction blister wound model on healthy subjec...
21058245 - Long-term follow-up of patients with esophageal replacement by reversed gastric tube.
8645075 - The role of a defective lower esophageal sphincter in the clinical outcome of treatment...
17669855 - Long-term follow-up after endocardial radiofrequency modified nitta procedure for conco...
21728705 - Practice-based evidence: patients who did not respond to group analysis.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-25
Journal Detail:
Title:  Skin pharmacology and physiology     Volume:  25     ISSN:  1660-5535     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101188418     Medline TA:  Skin Pharmacol Physiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  73-77     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Department of Dermatology, University Medicine, Ernst Moritz Arndt University, Greifswald, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Intrathecal Injection of Metabotropic Glutamate Receptor Subtype 3 and 5 Agonist/Antagonist Attenuat...
Next Document:  Race-ethnic differences of sleep symptoms in an elderly multi-ethnic cohort: the Northern Manhattan ...