Document Detail

Kinetic determination of sotalol by oxidation with sodium vanadate.
MedLine Citation:
PMID:  2100218     Owner:  NLM     Status:  MEDLINE    
A kinetic method is described for the determination of sotalol. The method uses 0.033 M sodium vanadate to oxidize sotalol in 4 M sulphuric acid. The solution is heated at 90 degrees C and the absorbance is measured at 750 nm at a fixed time of 30 min. The concentration (c) of sotalol is calculated from the absorbance (A) by the equation: A = 0.04 + 0.0015625 c.
S M Sultan; A M Bukhari; H Perzanowski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pharmaceutical and biomedical analysis     Volume:  8     ISSN:  0731-7085     ISO Abbreviation:  J Pharm Biomed Anal     Publication Date:  1990  
Date Detail:
Created Date:  1991-08-19     Completed Date:  1991-08-19     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  8309336     Medline TA:  J Pharm Biomed Anal     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  569-71     Citation Subset:  IM    
Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.
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MeSH Terms
Sotalol / analysis*
Sulfuric Acids
Reg. No./Substance:
0/Sulfuric Acids; 0/Vanadates; 3930-20-9/Sotalol; 7664-93-9/sulfuric acid

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