Document Detail

Kinematic analysis of facial behaviour in patients with schizophrenia under emotional stimulation by films with "Mr. Bean".
MedLine Citation:
PMID:  18071625     Owner:  NLM     Status:  MEDLINE    
In schizophrenic patients, motor functioning is substantially disturbed. Kinematic analysis is useful in examining this motor dysfunction. Using kinematic analysis, we aimed to investigate facial movement in schizophrenic patients responding to humorous film stimuli ("Mr. Bean"). Ultrasound markers were attached to pre-defined facial points while subjects watched a funny film sketch. The study included 21 schizophrenic in-patients (13 men, 8 women; mean (S.D.) age: 32.1 (10.4) years) and 30 healthy individuals (12 men, 18 women; mean (S.D.) age: 35.7 (11.0) years). Unmedicated schizophrenic patients showed an abnormally high initial velocity of laughing (IV), while patients treated with typical neuroleptics demonstrated an abnormally low IV. There was a significant positive correlation between severity of negative symptoms and IV. Kinematical analysis of facial movement using IV could help to distinguish subclinical Parkinsonian syndromes induced by typical neuroleptics from negative symptoms of schizophrenia.
Georg Juckel; R Mergl; A Prässl; P Mavrogiorgou; H Witthaus; H J Möller; U Hegerl
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European archives of psychiatry and clinical neuroscience     Volume:  258     ISSN:  0940-1334     ISO Abbreviation:  Eur Arch Psychiatry Clin Neurosci     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-08-07     Completed Date:  2008-09-30     Revised Date:  2009-05-11    
Medline Journal Info:
Nlm Unique ID:  9103030     Medline TA:  Eur Arch Psychiatry Clin Neurosci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  186-91     Citation Subset:  IM    
Westphalian Center Bochum, Psychiatry, Psychotherapy, Psychosomatic Medicine Clinic of the Ruhr-University Bochum, Bochum, Germany.
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MeSH Terms
Affective Symptoms / drug therapy,  physiopathology,  psychology*
Antipsychotic Agents / therapeutic use
Case-Control Studies
Emotions / physiology*
Facial Expression*
Laughter / physiology,  psychology*
Motion Pictures as Topic
Psychiatric Status Rating Scales
Reference Values
Schizophrenia / drug therapy*,  physiopathology
Schizophrenic Psychology*
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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