Document Detail


Kimura's disease with generalized lymphadenopathy demonstrated by positron emission tomography scan.
MedLine Citation:
PMID:  16847367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kimura's disease is a chronic inflammatory disorder that occurs mainly in Asian patients. Most imaging studies focus on the loco-regional involvement of this disorder. Images of the whole body fluorine-18 fluorodeoxyglucose positron emission tomography (18F-FDG PET) scan have not been reported in the literature before. The possibility of lymphoid clonality is also discussed frequently despite its clinically benign course. We present a patient of Kimura's disease initially assessed by whole body 18F-FDG PET study and proved by pathologic findings. 18F-FDG-PET scan showed diffusely intense uptake in the neck, axillary, pelvic and inguinal nodal regions bilaterally, as well as in the mediastinal, celiac region. The flow cytometric analysis of lymph node tissue confirmed the absence of clonality. The image of 18F-FDG-PET in Kimura's disease can closely resemble that seen in neoplastic disorders such as lymphoma or metastatic lymphadenopathy. It should be taken into consideration as a differential diagnosis for a generalized lymphadenopathy.
Authors:
Tso-Fu Wang; Shu-Hsin Liu; Chih-Hao K Kao; Sung-Chao Chu; Ruey-Ho Kao; Chi-Cheng Li
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-07-18
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  45     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2006  
Date Detail:
Created Date:  2006-07-18     Completed Date:  2006-09-15     Revised Date:  2006-11-20    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  775-8     Citation Subset:  IM    
Affiliation:
Division of Oncology and Hematology, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan, ROC.
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MeSH Terms
Descriptor/Qualifier:
Angiolymphoid Hyperplasia with Eosinophilia / pathology,  radionuclide imaging*
Biopsy / methods
Female
Flow Cytometry
Fluorodeoxyglucose F18 / diagnostic use
Humans
Lymphatic Diseases / pathology,  radionuclide imaging*
Middle Aged
Neck
Positron-Emission Tomography / methods*
Radiopharmaceuticals / diagnostic use
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

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